Where is the most dangerous spot on plane? Opinions vary. Actually the answer largely depends on certain occasions.
As a general rule, the nose is safer than the tail with a comparison of survival possibility of 65% to 53%. Tail is always the most fragile part of the body. In other words, seats in first class and business class are less risky. Though the wings carry the balance device and the stable system, they don’t secure the middle part of cabin because it is also where the engine locates.
When the plane landing, however, things become the opposite because the nose is lower.
seats by exits survival rate 65%
aisle seats survival rate 64%
window seats survival rate 58%
back seats survival rate 53%
(reference: Yangtze Evening Paper)